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Second to the liver, the kidney is the most vulnerable organ due to its ability to filter large amount of blood and contribution to the body's homeostasis by eliminating metabolic waste products

Bilirubin was also found to promote growth arrest in the cultures of human vascular smooth muscle primary cells stimulated by serum

Physiol Plant 107:294302 Kocsy G, von Ballmoos P, Regsegger A, Szalai G, Galiba G, Brunold C (2001) Increasing the glutathione content in a chilling-sensitive maize genotype using safeners increased protection against chilling-induced injury

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HS is caused by diverse mutations that lead to an insufficiency of membrane skeletal components